MRGN are multi-resistant, Gram-negative rod bacteria (e.g. Escherichia coli or Klebsiella pneumoniae) resistant to several classes of antibiotics. The term MRGN thus indicates that a bacterium is multi-resistant.
ESBL (extended-spectrum beta-lactamase) are bacterial enzymes that make bacteria insensitive to β-lactam antibiotics. The term not only describes the fact that the bacteria are antibiotic-resistant, but it also explains how bacteria become insensitive to antibiotics. Therefore, the name ESBL gives information about the type of underlying resistance mechanism.